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Topical Antihistamines

Clean the Sky - Positive Eco Trends & Breakthroughs

PBZ OTC is the First New Topical Antihistamine in 50 Years

— April 7, 2025 — Lifestyle
PBZ OTC is the first new topical antihistamine in half a century and this innovative medicine cabinet staple is launching to provide fast, safe and effective relief from the pain and discomfort associated with itching onset by insect bites, poison ivy, sunburn, and more.

The family-friendly itch relief solution is suitable for ages two and up, and it sets itself apart from other topical antihistamines by being safe to use alongside oral allergy medications such as Benadryl. PBZ OTC is a gentle, steroid-free formula that manages itching without limiting options for families, all while being non-greasy, quick to absorb and easy to take on the go without worry of side effects like drowsiness.

In the Immediate Relief Category, PBZ OTC was been named Product of the Year 2025.
Trend Themes
1. Rapid Innovation in Topical Treatments - The development of PBZ OTC marks a breakthrough in the topical antihistamine space, highlighting a move towards faster-acting, safer, and more diverse skin relief options after decades.
2. Steroid-free Itch Relief Products - There is a rising demand for steroid-free solutions as demonstrated by PBZ OTC, which appeals to health-conscious consumers seeking effective, gentle relief.
3. Multi-compatibility Medications - PBZ OTC's compatibility with oral allergy medications illustrates a trend towards creating products that integrate seamlessly with existing healthcare routines.
Industry Implications
1. Pharmaceuticals - Pharmaceutical companies are undergoing a shift as innovations like PBZ OTC open avenues for topical antihistamines with enhanced efficacy and user friendliness.
2. Consumer Healthcare - The consumer healthcare industry is capitalizing on the rising demand for non-greasy, immediate relief products that cater to family-friendly needs.
3. Over-the-counter Medication - PBZ OTC's release into the OTC market highlights a trend towards providing accessible and innovative solutions without requiring prescriptions.
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